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Just like Barcelona, Real Madrid will also struggle hard to bounce back from the mid-week’s defeat against Sevilla in La Liga.
Three first half goals from Andre Silva and Wissam Ben Yedder saw Madrid off at the Ramon Sanchez Pizjuan Stadium.
Meanwhile, Atletico Madrid put three goals past Huesca on Tuesday courtesy of Antoine Griezmann, Thomas Partey and the Spaniard Koke strikes.
With both Barcelona and Real Madrid losing during the mid-week, Real remain second in the La Liga table leveling on points with Barcelona,with Atletico being the third.
Real Madrid have injury concerns of Marcelo who picked up a calf injury during the Sevilla clash and has been confirmed out of tomorrows fixture.
Dani Carvajal will be welcomed back in the starting eleven after being rested against Sevilla. Nacho is expected to come into the team to replace the injured Marceloa.
For Atletico Madrid, Jose Gimenez is a minor doubt but should still start in defence. Lucas may be preferred to Filipe Luis at left-back while Rodri should fill in for Thomas in midfield.
Marc Casemiro will pattern with Toni Kroos and Luka Modric either side of him to bolster the midfield.
Marco Asensio, Karim Benzema and Gareth Bale will be expected to lead the attack against a strong defensive side Atletico Madrid.
Head to Head statistics show Atletico Madrid being unbeaten in 4 matches against Real Madrid with the last 3 being draws. Altetico are also unbeaten on their last 5 league visits to the Bernabeu having grabbed three wins and drawing twice.