Manchester United will be hosting La Liga club Valencia in the UEFA Champions League fixture on Tuesday at Old Trafford.
Pogba will be handed a starting position in the line-up after scoring twice in the 3-0 Champions League win over Young Boys.
Having beaten Young Boys 3-0 in the match group opener, Manchester United will need to add on other three points if they are to maintain themselves on the top of group H.
The Red Devils need to win this one having flattered in the last fixtures in all competitions including a 1-1 Premier League draw against Wolves, EFL Cup exit at home to Derby and a 3-1 loss to West Ham last Saturday.
Pogba will be handed a starting position in the line-up after scoring twice in the 3-0 Champions League win over Young Boys.
Alexis Sanchez may also be welcomed in the starting line-up after the Chilean was withdrawn from the weekend’s squad against West Ham.
Provisional squad: De Gea, Grant, Romero, Valencia, Dalot, Darmian, Young, Shaw, Smalling, Jones, Bailly, Lindelof, Pogba, Fellaini, Herrera, Mata, Matic, Pereira, Fred, McTominay, Lingard, Lukaku, Martial, Sanchez, Rashford
The two sides have met eight times previously, with United winning two games, Valencia one, and the teams sharing five draws.
The two sides last met was in the 2010-11 group stages, with United winning 1-0 in Spain before a 1-1 draw at Old Trafford
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