Atletico Madrid host Real Betis having picked three points in the mid-week from Monaco in the UEFA Champions League.
Meanwhile, the same to Real Betis, they were also successful in Europa League day two when they beat Dudelange 3-0 in Europa League on Thursday.
Real Betis has impressed in the last three games in all competitions by collecting all the 9 points. Real Betis has an outstanding clean sheets in 7 matches in their last 8 in all competitions.
Real Betis manager Quique Setien has lost four and drew one in his career against Atletico Madrid. Atletico Madrid has finally caught up having started badly, with 4 wins in 5 games in all competitions.
Last season two meetings saw only one goal scored in total with a few goal scoring chances corrected. Atletico Madrid have a perfect form with Betis having won 9 of the last 11 games.
Meanwhile, Spanish forward Diego Costa has failed to find the back of the net in the last 16 league games.